Beckmann

Regrouping of oximes to produce amidi acids using acids.

In reaction can engage oximes of aliphatic, aromatic, heterocyclic and mixed ketones.

Beckmann-Champnann regroupment - regrouping of RR'C=NOR" to oximes.

Werner regroupment - obtaining nitryles from ketooximes.

Also see Semmler-Wolff-Schroeter, Curtius, Lossen, Neber, Tiemann and Chapmann.

Bibliography

• Beckmann E., Ber., 1886, 19, 988; 1887, 20, 1507.
• Vinnik M. I., Zarahani N. G., Usp. himii, 1967, 36, 167.
• Jackson V. N., J. Org. Chem., 1970, 35, No.4, 875.
• McCullogh J. D. e.a., J. Am. Chem. Soc., 1972, 94, 874.
• Savva A., Martinov V. F., ZhOH, 1974, 44, No.7, 1655-1656.
• OR, 11, 7; RIMIOS, 3, 1655-1656.