Diels-Alder

Synthesis of cyclic compounds from 1,4-dienes and alkenes (dienophile).

The diene can be cyclic, acyclic or heterocyclic or it can contain the following fragments:

See also Wagner-Jauregg.

Bibliography

• Diels O., Alder K., Ann., 1928, 460, 98; Ann., 1929, 470, 62; Ber., 1929, 64, 2081, 2087.
• Martin J. G., Hill R. K., Chem. Rev., 1961, 61, 537.
• Hofmann H. M. R., Angew. Chem., 1969, 81, 597.
• McCabe J. R., Eckert Ch. A., Acc. Chem. Res., 1974, 7, No.8, 597.
• Ingold, 568; OR, 4, 7, 86; 5, 93.