Schotten-Baumann

Acylation of alcohols and amines with acyl hlorides in water solution.

The yield of the reaction is 60-90%.

Also see Einhorn, Galat-Elion, Doronow-Theidel, Hinsberg and Chattaway.

Bibliography

• Schotten C., Ber., 1884, 17, 2544.
• Baumann E., Ber., 1886, 19, 3218.
• Sonntag N. O. V., Chem. Rev., 1953, 52, 272.
• Tsuchiga M. e.a., Bull. Chem. Soc. Japan, 1969, 42, 1756.
• Tsuda Minoru e.a., Makromol. Chem., 1973, 167, 183.
• Houben-Weyl, 8, 545; 11/2, 478.