Welcome to the official homepage of Marina Stefova

 

 

 

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Marina Stefova

Date of birth: 08. 05. 1969
Place of birth: Skopje - Macedonia
Nationality: Macedonian
Marital status: married

E-mail: marinaiv@iunona.pmf.ukim.edu.mk
Address at work: Arhimedova 5
1000 Skopje, Macedonia
Telephone: +(389-2 ) 324-9934; Fax: +(389-2) 322-6865

Education:

  • PhD: Development of HPLC methods for identification and quantification of flavonoids in plant material and plant products, University Sts. Cyril and Methodius, Faculty of Natural Sciences & Mathematics in Skopje, 2001
  • MSc: Determination of vitamin B12 in pharmaceutical preparations by electrothermal atomic absorption spectrometry and high performance liquid chromatography, Faculty of Natural Sciences & Mathematics in Skopje, 1997
  • BSc: Infrared spectra of rubidium diaquatetrachloronickelate(II) and rubidium monoaquapentachloroferrate(II), Faculty of Natural Sciences & Mathematics in Skopje, 1992

Teaching experience:

  • Practical (laboratory) work in Analytical chemistry, Instrumental analysis and Environmental analysis
  • Lectures of Instrumental analysis, Trace analysis and Methodics in teaching chemistry

Areas of research interests

  • assay of flavonoids in plant material using chromatographic methods (HPLC, TLC, column chromatography);
  • identification and quantification of phenolic compounds with antioxidant activity in food (berry fruits, grapes, juices, wines)
  • development and validation of analytical methods for quantitative determination of flavonoids;
  • quantitative structure-HPLC retention relationships;
  • development of procedures for drug analysis in biological fluids by HPLC
  • environmental analysis using chromatographic methods (HPLC and GC).

Participation in projects (in last five years):

  • Chemotaxonomic, phytochemical and pharmacognostic investigation of the species: TEUCRIUM, CALAMINTHA, ACINOS, SATUREJA, CLINOPODIUM and MICROMERIA (LAMIACEAE) in the flora of Republic of Macedonia, national project (1999-2001) , participant.
  • Chemical characterization of wild-growing medicinal and aromatic plants from Lamiaceae family and evaluation of the possibilities for their cultivation, Macedonian-Bulgarian bilateral research project (2005-2007), coordinator.
  • Development of analytical methods for determination of traces of metals and drugs in biological samples, national project (2006-2009), participant
  • Teaching and learning bioanalysis, CEEPUS (Central European Exchange Program for University Studies) CII-HU-0010-01-0607, 2006-2007, participant.

Selected published articles (most important):

  1. 1. S. Kulevanova, M. Stefova, T. Stafilov, HPLC IDENTIFICATION AND DETERMINATION OF FLAVONE AGLYCONES IN HELICHRYSUM PLICATUM DC. (ASTERACEAE), Pharmazie 55, 5-7 (2000).
  2. 2. S. Kulevanova, M. Stefova, G. Stefkov, T. Stafilov, IDENTIFICATION, ISOLATION AND DETERMINATION OF FLAVONES IN ORIGANUM VULGARE FROM MACEDONIAN FLORA, J. Liq. Chrom. & Rel. Technol., 24, 589-600 (2001).
  3. 3. M. Stefova, S. Kulevanova, T. Stafilov, ASSAY OF FLAVONOLS AND QUANTIFICATION OF QUERCETIN IN MEDICINAL PLANTS BY HPLC WITH UV-DIODE ARRAY DETECTION, J. Liq. Chrom. & Rel. Technol., 24, 2283-2292 (2001).
  4. 4. D. Zendelovska, T. Stafilov, M. Stefova, OPTIMIZATION OF A SOLID-PHASE EXTRACTION METHOD FOR DETERMINATION OF INDAPAMIDE IN BIOLOGICAL FLUIDS USING HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY, J. Chromatogr. B., 788(1), 199-206 (2003).
  5. 5. D. Zendelovska, T. Stafilov, M. Stefova, HIGH-PERFORMANCE LIQUID CHROMATOGRAPHIC DETERMINATION OF DILTIAZEM IN HUMAN PLASMA AFTER SOLID-PHASE AND LIQUID-LIQUID EXTRACTION, Anal. Bioanal. Chem., 376, 848-853 (2003).
  6. 6. M. Stefova, T. Stafilov, S. Kulevanova, HPLC ANALYSIS OF FLAVONOIDS, in Encyclopedia of Chromatography (J. Cazes, Ed.), Marcel Dekker, Inc., (2003).
  7. 7. M. Stefova, V. Ivanova, I. Muratovska, IDENTIFICATION AND QUANTIFICATION OF Bis-GMA AND TEG-DMA RELEASED FROM DENTAL MATERIALS BY HPLC, J. Liq. Chrom. & Rel. Technol., 28(2), 289-295 (2005).
  8. 8. N. Ristovska, M. Stefova, F. Anastasova, RP-HPLC METHOD FOR SIMULTANEOUS DETERMINATION OF THIOBENZANILIDE AND ITS OXIDATION PRODUCTS: MONITORING THE OXIDATION OF THIOBENZANILIDE WITH JONES' REAGENT, J. Liq. Chrom. & Rel. Technol., 28(15), 2391-2401 (2005).
  9. 9. T. Kadifkova Panovska, S. Kulevanova, M. Stefova, IN VITRO ANTIOXIDANT ACTIVITY OF SOME TEUCRIUM SPECIES (Lamiaceae), Acta Pharm. 55, 207-214 (2005)
  10. 10. M. Stefova, T. Stafilov, S. Kulevanova, G. Stefkov, V.S. Bankova, QSRR OF FLAVONES-EVALUATION OF SUBSTITUENT CONTRIBUTION TO RP HPLC RETENTION, J. Liq. Chrom. & Rel. Technol. 30(8), 1035-1049 (2007).
  11. 11. B. Janeska, M. Stefova, K. Alipieva, ASSAY OF FLAVONOID AGLYCONES FROM SPECIES OF THE GENUS SIDERITIS (LAMIACEAE) FROM MACEDONIA WITH HPLC UV DAD, Acta Pharm. (2007) in press.
  12. 12. E. Kostadinova, K. Alipieva, M. Stefova, T. Stafilov, D. Antonova, Lj. Evstatieva, V. Matevski, S. Kulevanova, G. Stefkov, V. Bankova, CHEMICAL COMPOSITION OF THE ESSENTIAL OILS OF THREE Micromeria SPECIES GROWING IN MACEDONIA AND BULGARIA, Maced. J. Chem. Chem. Eng. (2007) in press.

Books:

  1. L. Šoptrajanova, M. Stefova, I. Kuzmanovski, IZVORI I KORISTENJE NA HEMISKI INFORMACII, Prosvetno delo, Skopje, 1999.
     

 

Institute of Chemistry